synthetic biology

Platforms for Genetic Design Automation

Crucial to the success of synthetic biology is the development of platforms for genetic design automation (GDA). This chapter presents the current state-of-the-art in GDA tools. This chapter also briefly describes the standards used for data …

Modeling and design automation of biological circuits and systems

Circuit designers are increasingly more drawn to challenges in modeling and designing biological circuits and systems. While the principles of biological organization and architecture resemble those in systems that engineers are designing, the …

Utilizing stochastic model checking to analyze genetic circuits

When designing and analyzing genetic circuits, researchers are often interested in the probability of the system reaching a given state within a certain amount of time. Usually, this involves simulating the system to produce some time series data and …

Genetic design automation

Electronic design automation (EDA) tools have facilitated the design of ever more complex integrated circuits each year. Synthetic biology would also benefit from the development of genetic design automation (GDA) tools. Existing GDA tools require …

The Design of a Genetic Muller C-Element

Synthetic biology uses engineering principles to design circuits out of genetic materials that are inserted into bacteria to perform various tasks. While synthetic combinational Boolean logic gates have been constructed, there are many open issues in …