Multiple input changes can cause unwanted switching variations, or glitches, in the output of genetic combinational circuits. These glitches can have drastic effects if the output of the circuit causes irreversible changes within or with other cells …
Synthetic biology builds upon genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. When designing a synthetic system, synthetic biologists need to exchange information about …
People who are engineering biological organisms often find it useful to communicate in diagrams, both about the structure of the nucleic acid sequences that they are engineering and about the functional relationships between sequence features and …
SynBioHub is a repository for synthetic genetic designs represented in the Synthetic Biology Open Language (SBOL). To integrate SynBioHub into more synthetic biology workflows, its data processing capabilities need to be expanded. To this end, a …
The Synthetic Biology Open Language (SBOL) is a community-developed data standard that allows knowledge about biological designs to be captured using a machine-tractable, ontology-backed representation that is built using Semantic Web technologies. …
Synthetic biology is applying engineering concepts to biological processes to enable genetic circuit designs, among other applications. As more biological parts are being discovered, it is vital to have an automated procedure to allow complex circuit …
Synthetic biology is an engineering discipline in which biological components are assembled to form devices with user-defined functions. As in any engineering discipline, modeling is a big part of the design process, since it helps to predict, …
Synthetic Biology is an emerging discipline which uses engineering principles to shape biological behavior. The Synthetic Biology Open Language (SBOL) is a standard for describing biological constructs which enables engineering workflows that …