Synthesis of Genetic Circuits from Graphical Specifications

Abstract

EDA tools have facilitated the design of ever more complex integrated circuits each year. Synthetic biology would also benefit from the development of genetic design automation (GDA) tools. Existing GDA tools require biologists to design genetic circuits at the molecular level, roughly equivalent to designing electronic circuits at the layout level. Analysis of these circuits is also performed at this very low level. This paper presents a first step at developing a GDA tool that supports higher levels of abstraction. In particular, this paper describes a graphical specification language from which molecular descriptions can be synthesized. These descriptions can then be abstracted to facilitate efficient analysis. I.

Publication
2008 Int. Workshop on Logic Synthesis
Nathan Barker
Nathan Barker
Southern Utah University, Department Chair of Computer Science & Information Systems
Hiroyuki Kuwahara
Hiroyuki Kuwahara
King Abdullah University of Science and Technology, Computational Bioscience Research Center Research Scientist
Curtis Madsen
Curtis Madsen
Sandia National Laboratories, R&D S&E, Computer Science

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