genetic design automation

SBOLCanvas: A Visual Editor for Genetic Designs

SBOLCanvas is a web-based application that can create and edit genetic constructs using the SBOL data and visual standards. SBOLCanvas allows a user to create a genetic design visually and structurally from start to finish. It also allows users to …

Design of Asynchronous Genetic Circuits

Most digital electronic circuits utilize a timing reference to synchronize the progression of signals and enable sequential memory elements. These designs may not be realizable in biological substrates due to the lack of a reliable high-frequency …

Introduction to the Special Issue on Computational Synthetic Biology

The goal of this special issue is to introduce the field of computational synthetic biology to engineers and computer scientists. The first article gives an introduction to the key biological principles and experimental techniques that support …

Computational Synthetic Biology: Progress and the Road Ahead

Synthetic biology promises to leverage engineering principles to enable model-based design of genetic circuits. To be successful, advancements are needed in both experimental and computational methods to support this new approach. This paper focuses …

Platforms for Genetic Design Automation

Crucial to the success of synthetic biology is the development of platforms for genetic design automation (GDA). This chapter presents the current state-of-the-art in GDA tools. This chapter also briefly describes the standards used for data …

Genetic design automation

Electronic design automation (EDA) tools have facilitated the design of ever more complex integrated circuits each year. Synthetic biology would also benefit from the development of genetic design automation (GDA) tools. Existing GDA tools require …